The City Guest House, Rome, is a modern property set in the city's Tuscolona area, next to the shopping district and 500 metres from Parco degli Acquedotti.

The 25 guestrooms are decorated in light colours with patterned fabrics, wooden flooring and wood furniture. Modern amenities include air conditioning, satellite television, private bathrooms with hairdryers and showers. Guests of the City Guest House can relax in the bright and modern reception area, fitted with sofas and complimentary Internet access services. Practical amenities include pay parking onsite, breakfast services (fee), and a 24 hour front desk. Those wishing to sightsee in Rome can seek tour assistance from the hotel's multilingual staff.

The City Guest House in Rome is close to many attractions for guests wishing to explore the local area; Tuscolana's shopping centre is 100 metres away, Cinecitta is one kilometre away, and San Giovanni is at a distance of two kilometres.

The nearest airport to the hotel is Ciampino Airport, which is 15 kilometres away at an approximate driving time of 15 minutes.

Buses run regularly from the airport to Anagnina subway station. From here, take the subway to Numidio Quadrato. The hotel is 100 metres away. The efficient integrated transportation system includes buses, trams, subway (metro) and suburban trains. Tickets should be bought before boarding and are available from ATAC ticket machines and all tobacconists.