The Hotel Globus is located on the north side of Florence by San Lorenzo market, 300 metres from the city's breathtaking Duomo. The hotel's 23 rooms have contemporary dark wood furniture, with pastel walls, soft lighting and art prints. All include safes, minibars, cable TV and high speed Internet connections. Some rooms have views of the adjacent Medici Chapel. Breakfast is served each morning and guests can enjoy a drink, cocktail or coffee at the B.B. bar and lounge, with its sofas, armchairs, glass tables and flat screen television. The 24 hour front desk can assist with general queries, dry cleaning services and photocopy facilities. Newspapers are available for guests in the lobby and there is also a free high speed Internet point. Visitors are within easy walking distance of many of Florence's cultural treasures including the Duomo, 300 metres from the hotel, and the Palazzo Vecchio, one kilometre away with its public square home to an actual size replica of Michelangelo's famed sculpture of David. The real one is housed in the Accademia Gallery, one kilometre from the hotel.

Santa Maria Novella Station is 500 metres from the hotel and Florence Airport is six kilometres (four miles) away.